心脏粉样性查和心脏衰竭患者的管理与保存的喷射部分:一个国际调查
Anastasia Shchendrygina1, Nathan Mewton2, David Niederseer3
1Department of Hospital Therapy 2, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
The American journal of cardiology
|October 31, 2024
概括
心脏 Amyloidosis (CA) 在心力衰竭中被低诊断,其中保留了喷射分数 (HFpEF). 全球医生调查显示,查,诊断和治疗方法各不相同,强调需要改善教育和获得治疗方法.
科学领域:
- 心脏病学 心脏病学
- 内部医学 内部医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 心脏粉症 (CA) 是心力衰竭 (HF) 的未被确诊的原因.
- 早期识别和治疗HF中的CA与保存的喷射分数 (HFpEF) 改善了患者的治疗结果.
- 目前在HFpEF患者中对CA的查和管理实践尚未在全球范围内标准化.
研究的目的:
- 评估全球医生对HFpEF患者的CA查和管理的方法.
- 确定医生在HFpEF中用于CA的当前诊断工具和治疗策略.
- 了解医生对CA疾病修饰疗法 (DMT) 的可用性和管理的看法.
主要方法:
- 在2023年5月至7月期间,在医生中进行了一项国际网络调查.
- 该调查收集了来自95个国家的1460名医生关于CA查,诊断和HFpEF患者的管理的数据.
- 数据分析的重点是查标准,一线诊断工具和治疗偏好.
主要成果:
- 只有10%的医生系统地查了所有HFpEF患者的CA;24%根本没有查.
- 左心室缩是最常见的查标准 (39%).
- 血清蛋白电泳与免疫固定和尿蛋白电泳或心脏MRI是常见的第一线诊断;CA DMT可供48%的医生使用.
结论:
- 在全球范围内,关于在HFpEF患者中进行CA查的必要性存在重大不确定性.
- 癌症的管理,特别是查和诊断,是高度异质的.
- 需要在HF社区中加强教育,改善获得CA特定的DMT的机会.
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