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Updated: Jun 9, 2025

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癌症相关突变对连接体结合和受体功能的影响 - - 对5-HT2C受体的一个例子

Chenlin Feng1, Rongfang Liu2, Reno Brooks2

  • 1Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, 2333 CC, Leiden, the Netherlands; Oncode Institute, 2333 CC, Leiden, the Netherlands.

European journal of pharmacology
|October 31, 2024
PubMed
概括

血清素5-HT2C受体中与癌症相关的突变显著改变了它的功能和连接体结合. 这些遗传变化影响受体信号传递,并可能影响向该受体的癌症治疗策略.

关键词:
5-HT ((2C) 受体的受体.癌症 癌症 癌症 癌症G蛋白结合受体的受体是G蛋白结合受体的受体.突变突变是一种突变.这是一种血清胺.

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