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Updated: Apr 14, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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一个纳米体工具箱,用于识别Cas9上的明显的位.

Jack Boylan1, Rebecca A Shrem1, Isabel C Vallecillo-Viejo2

  • 1Departments of Pharmacology, Vanderbilt University, Nashville, TN 37232, United States.

Journal of molecular biology
|October 31, 2024
PubMed
概括

研究人员开发了针对Streptococcus pyogenes Cas9的纳米体,这是基因工程中的一个关键工具. 这些纳米体有效地结合Cas9而不会抑制其DNA编辑功能,为科学研究提供了有价值的试剂.

关键词:
这就是Cas9的情况.皮托普比恩 (Epitope bin bin) 是一个表层层中的一个.纳米体是一个纳米体.

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Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
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