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Updated: Jun 9, 2025

Strategies for Assessing Autistic-Like Behaviors in Mice
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Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

871

在自闭症谱系障碍的临床前模型中,mTOR信号通路作为一种病理生理机制

Isabela Drehmer1, Júlio Santos-Terra2, Carmem Gottfried2

  • 1Translational Research Group on Autism Spectrum Disorder - GETTEA, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; National Institute of Science and Technology in Neuroimmunomodulation - INCT-NIM, Brazil; Autism Wellbeing and Research Development - AWARD - Initiative BR-UK-CA, Brazil; Psychiatry Molecular Laboratory, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil; Department of Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.

Neuroscience
|October 31, 2024
PubMed
概括

自闭症谱系障碍 (ASD) 涉及社会缺陷和刻板印象. 本综述强调了拉帕素 (mTOR) 途径的机制性标.

关键词:
动物模型动物模型自闭症谱系障碍 自闭症谱系障碍拉帕氨酸激酶酶的使用方法在mTOROR中使用mTOR.

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