中国绝经后妇女下垂体起源的人类胆管性淋巴激素:单中心回顾性研究
Yonghong Tian1, Long Zhang2, Jingping Li1
1Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China.
Taiwanese journal of obstetrics & gynecology
|October 31, 2024
概括
这项研究在中国绝经后妇女中确定了5.3 IU/L人类胆管性腺激素 (hCG) 的参考间隔. 卵泡刺激激素 (FSH) 水平可以帮助在这个群体中区分垂体hCG.
科学领域:
- 内分泌学 在内分泌学.
- 生殖医学 生殖医学
- 临床化学 临床化学
背景情况:
- 在绝经后的女性中,人体胆性淋巴激素 (hCG) 的升高会导致临床混乱.
- 从其他来源区分下垂体hCG至关重要,以避免不必要的治疗.
研究的目的:
- 分析中国绝经后妇女下垂体hCG的特征和相关因素.
- 为了确定hCG的参考间隔,以解决临床混乱.
- 确定分辨下垂体hCG的方法,避免有害的疗法.
主要方法:
- 对9796名接受hCG测量的个人进行了回顾性队列研究.
- 对hCG,卵泡刺激激素 (FSH) 和黄素化激素 (LH) 的血清度的分析.
- 进行了年龄分层分析和激素水平之间的相关性分析.
主要成果:
- 对hCG的上限参考区间被确定为5.3 IU/L.
- hCG,FSH和LH度与年龄没有显著的相关性.
- hCG与FSH (r=0.47) 和LH (r=0.53) 相对应适度,FSH显示出更好的临床适用性.
结论:
- 在55岁以上的女性中,hCG≥5.0 IU/L和≥5.3 IU/L的患病率分别为2.8%和2.3%.
- 在绝经后的妇女中,建议hCG 5.3 IU/L的值为积极结果.
- 在绝经后的妇女中,FSH ≥40 IU/L有助于区分垂体hCG,血清hCG在5.3至16 IU/L之间.
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