在骨折相关感染的DAIR程序-何时以及如何
Susanne Baertl1, Markus Rupp1, Volker Alt1
1Department of Trauma Surgery, University Medical Centre, Regensburg, Germany.
Injury
|October 31, 2024
概括
骨折相关感染 (FRI) 的手术治疗包括除菌抗生素和植入物保留 (DAIR) 或植入物交换. 最好的方法取决于感染持续时间,植入物稳定性和患者健康,以获得最佳的结果.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 生物材料科学 生物材料科学
背景情况:
- 骨折相关感染 (FRI) 在骨科手术中构成重大挑战.
- 目前的治疗策略缺乏标准化的指导方针,导致不同的临床结果.
研究的目的:
- 审查当前的治疗策略,以手术治疗骨折相关感染 (FRI).
- 确定为FRI选择适当的外科干预的关键考虑因素.
主要方法:
- 关于FRI治疗现有文献的叙事综述.
- 在FRI管理中影响外科决定的因素分析.
主要成果:
- 降解抗生素和植入物保留 (DAIR) 是首选的早期感染与稳定的植入物.
- 植入物交换 (单阶段或多阶段) 适用于复杂的病例,包括慢性感染,生物膜存在或先前治疗失败.
- 治疗选择以感染开始,植入物类型,病原体和宿主因素为指导.
结论:
- 对FRI的治疗选择需要仔细考虑多种临床因素.
- 需要进一步的研究,包括随机对照试验和标准化分类,以优化FRI管理.
- 了解生物膜动态和时间对治疗的影响对于未来的进展至关重要.
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