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Updated: Jun 9, 2025

Exploring Caspase Mutations and Post-Translational Modification by Molecular Modeling Approaches
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卡斯帕斯-2 是一种在蛋白质质量控制中通过凝结物介导的二维基基因酶

Yingwei Ge1, Lijie Zhou1,2, Yesheng Fu1

  • 1State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.

Nature cell biology
|November 1, 2024
PubMed
概括

卡斯帕-2 (CASP2) 在称为ubstressomes的压力颗粒中充当二维基因酶,去除多余的泛基因链,以防止蛋白质聚合和神经退行. 这种新的功能通过清除受损的蛋白质来维持细胞健康.

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