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Updated: Jun 9, 2025

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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独特的H3K9me3异染色体维护动态控制了多能细胞中不同的基因程序和重复

Jingchao Zhang1,2,3, Greg Donahue1,2,3, Michael B Gilbert2,4

  • 1Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Nature cell biology
|November 1, 2024
PubMed
概括

基因组H3氨酸9三甲基化 (H3K9me3) 异染色素稳定性在整个基因组中各不相同. 它的衰变涉及被动和活性机制,由黑色素蛋白1 (HP1) 和氨酸甲基转移酶 (KMTs) 调节.

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