在UDP-Gal/UDP-GalNAc 4-epimerase缺陷突变体中,O相关的糖化和LDL受体表达的可逆缺陷

Cell
|March 14, 1986
PubMed
概括

缺乏UDP-银河糖和UDP-N-乙银河胺4-表酶的仓鼠细胞突变体 (ldld) 不能合成必需的糖. 补充银河糖和GalNAc可以纠正所有糖化缺陷,包括LDL受体活性.

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