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脑卒中与相对脂肪量之间的关联:基于NHANESES的横截面研究

Yafang Zheng¹, Chunyuan Huang¹, Jing Jin¹

¹Liaoning University of Traditional Chinese Medicine, Shenyang, China.

Lipids in health and disease

|November 1, 2024

概括

较高的相对脂肪量 (RFM) 与较高的中风风险有关. 这一发现表明,RFM可能是预防中风和管理策略的宝贵工具.

科学领域:

心血管健康心血管健康
代谢健康代谢健康
流行病学流行病学

背景情况:

相对脂肪质量 (RFM) 是评估总体脂肪的新型指标.
调查RFM和中风发生之间的相关性对于公共卫生至关重要.
了解身体脂肪成分在心血管疾病中的作用是一个正在进行的研究领域.

研究的目的:

为了研究相对脂肪质量 (RFM) 和中风之间的关联.
要确定RFM是否是中风的独立预测因素.
探索RFM与中风关系中的潜在改变因素.

主要方法:

使用了国家健康和营养检查调查 (NHANES) 数据集 (2005-2018).
采用多项逻辑回归,子组分析,平滑曲线拟合和相互作用测试.
分析了来自35,842名参与者的数据,包括1,267例中风病例.

主要成果:

在RFM和中风之间发现了积极的关联 (OR=1.02,95% CI:1.01-1.03).
与最低四分位数相比,RFM最高四分位数的参与者中风的几率增加了44% (OR=1.44,95% CI:1.09-1.90).
年龄和体重指数 (BMI) 显著改变了RFM和中风之间的关联 (P的相互作用<0.01).

结论:

较高的相对脂肪质量显著与中风的几率增加有关.
电路风险管理可以作为评估中风风险的有价值指标.
进一步研究RFM在中风预防和管理中的作用是有必要的.

关键词:

心血管疾病是什么心血管疾病尼汉斯 (NHANES) 是一个名人.肥胖问题肥胖问题相对脂肪质量相对脂肪质量一次性中风,中风.

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