乳腺癌幸存者的身体活动和认知功能之间的关系:一个横截面分析
Sheri J Hartman1,2, Rong W Zablocki1, Rowena M Tam1
1Herbert Wertheim School of Public Health, UC San Diego, La Jolla, CA, United States.
Frontiers in Cognition
|November 1, 2024
概括
身体活动可以改善乳腺癌幸存者的自我报告认知能力,特别是更接近诊断的处理速度. 需要更多的研究来证实对客观测量的认知有好处.
科学领域:
- 在瘤学瘤学.
- 神经科学是一个神经科学.
- 康复 康复 康复 康复
背景情况:
- 癌症及其治疗通常会导致乳腺癌幸存者的长期认知能力下降.
- 身体活动是影响认知功能的潜在可修改因素.
- 现有研究表明,关于运动,认知和癌症治疗之间的关系的发现不一致.
研究的目的:
- 研究身体活动与乳腺癌幸存者的自我报告和客观测量的认知之间的关联.
- 探索癌症治疗是否能缓和身体活动和认知功能之间的关系.
主要方法:
- 在一项随机临床试验中利用了253名乳腺癌幸存者的基线数据.
- 通过神经认知测试和PROMIS认知能力问卷评估认知能力.
- 通过加速度计测量体力活动,穿了7天,并分析了医疗图表以获取治疗信息.
主要成果:
- 较高的中度至强度体力活动 (MVPA) 与更好的自我报告的认知能力 (p=0.012) 有关.
- 在MVPA和客观测量的认知领域之间没有发现任何显著的关联.
- 自诊断以来的时间调节了MVPA和处理速度之间的关系 (p=0.017).
结论:
- 在乳腺癌幸存者中,体力活动与自我报告的认知有关,但不是客观测量的认知.
- 身体活动对处理速度的好处可能在癌症诊断更接近时更加明显.
- 需要进一步的研究来确定最佳的身体活动干预措施,以提高癌症幸存者的认知能力.
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