相关实验视频

Updated: May 1, 2026

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Published on: May 26, 2015

使用非阻塞性通用血管镜和组织病理学估计外周动脉疾病的栓塞源

Sei Komatsu¹, Mitsuhiko Takewa¹, Chikao Yutani²

¹Department of Cardiology, Cardiovascular Center, Osaka Gyoumeikan Hospital, Osaka, Japan.

Journal of cardiology cases

|November 1, 2024

概括

来自大动脉斑块破裂的栓塞可能会恶化周围动脉疾病 (PAD). 这项研究确定了切割的大动脉作为患者PAD的来源,治疗阻止了疾病的进展.

科学领域:

心血管医学心血管医学
血管外科血管外科
干预性放射学干预性放射学

背景情况:

周围动脉疾病 (PAD) 可能会因源自大动脉的栓塞事件而恶化.
在PAD中确定精确的栓塞源是临床上具有挑战性的.
大动脉动脉样硬化和剖析是栓塞物质的潜在来源.

研究的目的:

在有右关动脉闭塞病史的患者中,确定复发性外周动脉疾病 (PAD) 的栓塞源.
调查大动脉斑块破裂和PAD恶化之间的关系.
评估内血管修复对导致PAD的大动脉剖析的疗效.

主要方法:

使用非阻塞性血管镜 (NOGA) 进行外周动脉和大动脉可视化和采样.
执行了大动脉和下肢动脉的计算机断层扫描血管学 (CTA).
从大动脉破裂和封闭的外围动脉中进行了斑块材料的比较分析.

主要成果:

在腹膜下腹动脉的大动脉剖析被确定为栓塞的来源.
在大动脉中观察到四个"气泡吊灯"断裂,从多个位置采集样本.
栓塞物质的最高同质性是在切割的下大动脉和封闭的关动脉之间发现的.
切割的大动脉的内血管移植成功地阻止了PAD的进展.

结论:

被剖析的内腹动脉是导致外周动脉疾病 (PAD) 栓塞的重要来源.
非阻塞性血管镜检查是有效的,用于识别主动脉和外围动脉的栓塞源.
大动脉解剖的内血管修复可以有效地管理栓塞性PAD.

关键词:

血管镜检查是对血管的检查.动脉瘤 (Atheroma) 是一种动脉瘤.血栓栓形成的原因是周围动脉疾病是什么?

更多相关视频

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

相关概念视频

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...