乌克兰的维生素D缺乏:一个多中心的横截面研究
Sofiia Shatylo1, Volodymyr Bogomaz1, Oleksii Babych2
1Department of Internal Medicine, Faculty of Dentistry, Bogomolets National Medical University, 9 Volodymyr Vynnychenko Str., 04053 Kyiv, Ukraine.
Global epidemiology
|November 1, 2024
概括
维生素D缺乏和不足在乌克兰很普遍,影响了儿童和成年人的很大一部分. 这项研究强调,迫切需要提高意识和干预策略,以改善乌克兰人口的维生素D状况.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于乌克兰维生素D状况的流行病学数据有限.
- 了解维生素D水平对于公共卫生倡议至关重要.
研究的目的:
- 为了确定维生素D缺乏在乌克兰的流行情况.
- 评估乌克兰人口的维生素D缺乏和足够水平.
主要方法:
- 这是一项多中心,横截面的研究,涉及11,462名参与者 (儿童和成人).
- 使用化学发光免疫测试测量血清25-基维生素D (25(OH) D) 水平.
- 标准化的切断线被用来定义维生素D缺乏,不足,充足和毒性.
主要成果:
- 中位数25(OH) D水平为65.4nmol/L.
- 维生素D缺乏是普遍存在的,不足影响了37%和缺乏 (严重和中度) 影响了所有参与者的26%.
- 维生素D缺乏的患病率在儿童 (1-17岁) 中为23.5%,在成年人 (≥18岁) 中为26%.
- 在4.2%的1-2岁儿童中,观察到有毒维生素D水平.
结论:
- 维生素D缺乏和不足在乌克兰是一个重大的公共卫生问题.
- 这些发现强调了需要有针对性的干预措施,以改善全国维生素D状况.
相关概念视频
01:23Role of Skin in Vitamin D Synthesis
5.0K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.0K
01:25Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
01:22Connective Tissue Cell Types
3.1K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.1K