响应声学风湿测量用于实时评估出血患者的血凝血
Cheri Deng1, Weiping Li1, Connor Bunch2
1University of Michigan.
Research square
|November 1, 2024
概括
共振声学类风湿学 (RAR) 可以评估出血患者的血凝固. 这种床边测试准确地预测了需要输血的血液产品,改善了静血管理.
科学领域:
- 生物医学工程 生物医学工程
- 血液学 血液学 血液学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 危及生命的出血需要快速的血液静止评估才能有效治疗.
- 目前用于表型凝血障碍的方法在关键情况下可能缺乏速度或灵敏度.
- 准确的静血分析对于指导血液成分和静血辅助疗法至关重要.
研究的目的:
- 评估共振声学类风湿测量 (RAR) 作为床边静血表型的新方法.
- 评估RAR参数与已建立的凝血试验 (TEG) 之间的相关性.
- 确定RAR在预测出血患者输血需求方面的有用性.
主要方法:
- 使用共振声学类风湿测量 (RAR) 来测量血粘弹性特性.
- 将RAR测量与临床凝血试验和全血血栓形成显微镜 (TEG) 进行了比较.
- 在RAR数据上训练了一个分类器,以预测新鲜冷血和冷沉积物的输血.
主要成果:
- RAR有效捕获了动态血凝固特征,取决于激活.
- RAR参数与TEG反应时间和功能性纤维素原显著相关.
- 基于RAR的分类器准确地预测了对特定血液产品输血的要求.
结论:
- 共振声学类风湿测量 (RAR) 是一个有希望的,作为一个快速的,床边工具,用于血液静止评估.
- 在出血患者中,RAR可以指导输血决策,从而有可能改善患者的治疗结果.
- 这项技术为在重症监护机构管理凝血纤维素溶解性疾病提供了一种新方法.
相关概念视频
01:30Equipments Used To Measure Blood Pressure
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
01:19Assessing Blood pressure using a doppler ultrasound
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
01:17Measurement of Blood Pressure
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
01:26Blood Studies I: ABG and VBG
Blood studies are critical in the medical field, enabling healthcare professionals to assess a patient's health status accurately. This page will focus on two significant blood studies: Arterial Blood Gas (ABG) and Venous Blood Gas (VBG).
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...