使用覆盖式气球可扩展支架进行大动脉缩的内血管治疗 - - 一项系统性审查和元分析
Fei He1, Zhongze Cao2, Chen Wang1
1Department of Vascular Surgery, Huaihe Hospital, Henan University, Kaifong, Henan, China.
Frontiers in cardiovascular medicine
|November 1, 2024
概括
被覆盖的气球可扩展支架 (CBS) 是安全有效的治疗大动脉缩 (CoA). 这一元分析显示了高的成功率,显著的血液动力学改善,以及可接受的并发症概况CBSs在COA患者.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械技术 医疗器械技术
背景情况:
- 大动脉缩 (CoA) 是一种先天性心脏缺陷,需要有效治疗.
- 气球扩张和支架是对COA的既定治疗方法.
- 在大型队列中,覆盖气球可扩展支架 (CBS) 的安全性和有效性的证据是有限的.
研究的目的:
- 评估CBS在治疗大动脉缩中的安全性和有效性.
- 评估手术成功率,血液动力学和解剖学益处,并发症和CBSs对CoA的中期结果.
- 为CoA提供关于CBSs的现有文献的综合元分析.
主要方法:
- 在PubMed,Embase和Cochrane图书馆数据库中进行系统的文献搜索.
- 对12项研究的元分析,包括411名接受CBS治疗的患者.
- 计算合并的手术成功率,并发症发生率,压力梯度和血压变化.
主要成果:
- 在Coa中植入CBS的程序成功率为100%.
- 观察到过干压梯度和静缩血压的显著降低.
- 与支架相关的 (2%),大动脉 (2%) 和接入部位 (3%) 的并发症的综合发病率较低.
结论:
- 被覆盖的气球可扩展支架植入是一种安全有效的治疗对主动脉的治疗方法.
- 证明了高的手术成功率和有利的血液动力学结果.
- 可接受的并发症发生率和较低的再缩率支持使用CBSs治疗CoA.
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