了解多囊性卵巢综合征的疼痛:健康风险和治疗有效性
Tess Cherlin1, Stephanie Mohammed1, Sasha Ottey2
1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, Philadelphia, PA, United States.
medRxiv : the preprint server for health sciences
|November 1, 2024
概括
多囊卵巢综合征 (PCOS) 显著影响女性,近20%的女性经历疼痛. 解决PCOS管理中的疼痛对于改善患者健康结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 生殖健康 生殖健康
- 疼痛管理 疼痛管理
背景情况:
- 多囊卵巢综合征 (PCOS) 是一种常见的内分泌疾病.
- 疼痛,包括经期不良和骨盆疼痛,是PCOS中未被认可的症状.
- 疼痛对PCOS患者的影响需要进一步调查.
研究的目的:
- 为了确定被诊断为PCOS的女性疼痛的患病率.
- 分析基于种族和PCOS药物使用的疼痛患病率.
- 评估PCOS,疼痛和未来健康结果之间的关联.
主要方法:
- 来自TriNetX全球网络的电子健康记录 (EHR) 的回顾性分析.
- 涉及120个医疗保健组织的7600多万名妇女.
- 针对健康结果计算的相对风险比率 (RR),按种族分层.
主要成果:
- 在患有PCOS的女性中,有19.21%报告疼痛.
- 在黑人/非洲裔美国人 (32.11%) 和白人 (30.75%) 妇女中观察到的疼痛患病率最高.
- PCOS和疼痛队伍在不孕症和肥胖症等疾病中增加了RR;PCOS药物与疼痛诊断的减少相关.
结论:
- 疼痛是多囊性卵巢综合征的重要并发症.
- 在PCOS相关的健康结果中存在种族差异.
- 将疼痛评估和管理整合到PCOS护理中,对于更好的患者结果至关重要.
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