表达驱动的遗传依赖揭示了精准医学的目标

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Updated: Jun 8, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Published on: August 25, 2023

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Abdulkadir Elmas1, Hillary M Layden2, Jacob D Ellis2

  • 1Department of Genetics and Genomic Sciences, Department of Artificial Intelligence and Human Health, Center for Transformative Disease Modeling, Tisch Cancer Institute, Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

bioRxiv : the preprint server for biology
|November 1, 2024
PubMed
概括

这项研究引入了BEACON,一种通过分析基因表达来找到新的精确瘤点的方法. 它确定了对瘤细胞存活至关重要的新型癌症标,提供了新的治疗途径.

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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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