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Updated: Jun 8, 2025

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

Published on: August 12, 2014

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外染色体DNA驱动的瘤基因空间异质性和质母细胞瘤的演变

Imran Noorani, Magnus Haughey, Jens Luebeck

    bioRxiv : the preprint server for biology
    |November 1, 2024
    PubMed
    概括

    外染色体DNA (ecDNA) 放大驱动着质母细胞瘤的进化和治疗耐药性. 早期检测ecDNA,特别是EGFR变异,可能为干预提供治疗窗口.

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