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Updated: Jun 8, 2025

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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NOTCH1驱动瘤可塑性和转移在肝细胞癌的转移

Katherine E Lindblad, Romain Donne, Ian Liebling

    bioRxiv : the preprint server for biology
    |November 1, 2024
    PubMed
    概括

    NOTCH1激活驱动肝癌的可塑性和肺转移,可以通过抑制VEGF和TGFß通路来向这些转移. 这项研究提出了一个新的小鼠模型,用于研究NOTCH1驱动的肝细胞癌 (HCC).

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