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Updated: Jun 8, 2025

Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia
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弧介于通过细胞外囊泡进行细胞间 tau 传输

Mitali Tyagi1, Radhika Chadha1, Eric de Hoog1

  • 1Department of Neurobiology, University of Utah, Salt Lake City, USA.

bioRxiv : the preprint server for biology
|November 1, 2024
PubMed
概括

神经元基因Arc将tau蛋白包装成细胞外囊泡 (EVs),这对于其在阿尔茨海默氏症等神经退行性疾病中细胞间传播至关重要. 弧形缺陷阻止了传输,并防止了神经元的损失.

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