Abl 激酶调节了独立于Crk酸化的FGF信号传递,以防止彼得斯异常

Hao Wu1, Yingyu Mao1, Qian Wang1

  • 1Departments of Ophthalmology, Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.

概括

Abl酶调节FGF信号以控制细胞张力,为彼得斯异常,先天性角膜不透明性提供了一个新的治疗点. 这项研究通过确定涉及的关键信号通路来澄清病情的分子基础.

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