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Updated: May 8, 2026

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在人体活体中,人类Glp1r A316T变体的功能概况和结构特征

Liliane El Eid, Kieran Deane-Alder, Roxana-Maria Rujan

    bioRxiv : the preprint server for biology
    |November 1, 2024
    PubMed
    概括

    葡萄糖类-1受体 (GLP-1R) 基因的特定遗传变异,A316T,影响2型糖尿病风险,并改变对GLP-1受体激活剂 (GLP-1RAs) 的反应. 这种变体会影响基底受体活性和药物疗效.

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