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Updated: Jun 8, 2025

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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更多的T细胞受体对癌症中的RAScue?

Eric Tran

    The Journal of clinical investigation
    |November 1, 2024
    PubMed
    概括

    研究人员确定了有希望的T细胞受体 (TCRs) 用于针对KRAS G12V突变的TCR基因治疗 (TCR-T). 这些来自健康捐赠者和癌症患者的TCR显示出治疗KRAS G12V阳性癌症的潜力.

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