高保留率和快速长效注射剂预暴露预防的坚持 实施在城市安全网诊所人口中
Matthew A Spinelli1, Ezra Bisom-Rapp2, Megan J Heise1
1Division of HIV, ID, and Global Medicine, University of California, San Francisco, United States.
概括
在安全网计划中,长期作用的暴露前预防 (PrEP) 注射显示出高的准时遵守率 (85%) 和保留率 (83%). 这种方法,即提供当天启动和包裹服务,即使对住房不安全的个人来说也是有效的.
科学领域:
- 公共卫生 公共卫生
- 预防传染病 预防传染病
- 药理学 药理学是指药理学的学科.
背景情况:
- 口服暴露前预防 (PrEP) 已证明在预防艾滋病毒感染方面具有有效性.
- 在口服PrEP疗程的坚持和保留方面仍然存在挑战.
- 长效注射PrEP提供了一个潜在的替代方案来解决粘附障碍.
研究的目的:
- 在安全网环境中评估低障碍,长效注射PrEP程序的有效性和保留.
- 评估同一天/第二天启动和包裹服务对计划结果的影响.
- 在计划中确定住房不安全人口中的保留率.
主要方法:
- 实施一个低障碍的,长效的注射PrEP程序.
- 为符合条件的个人提供同日或第二天启动的便利.
- 提供落入,包裹服务,以支持参与者.
- 追踪注射坚持性和6个月保留率.
主要成果:
- 85%的长效注射PrEP药物按时使用.
- 该计划的6个月保留率为83%.
- 在收到包裹服务的住房不安全的个人中观察到类似的保留率.
结论:
- 一个低障碍的,长效的注射PrEP程序可以实现高坚持和保留.
- 同一天启动和全面的支持服务对于计划的成功至关重要.
- 扩大长效PrEP是有必要的,以改善艾滋病毒预防工作.
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