戒烟和发生心血管疾病
Jun Hwan Cho1,2, Seung Yong Shin3, Hoseob Kim4
1Division of Cardiology, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Republic of Korea.
JAMA network open
|November 1, 2024
概括
戒烟显著降低了心血管疾病 (CVD) 的风险,尤其是轻度吸烟者. 与从未吸烟者相比,重度前吸烟者可能需要超过25年才能使心血管疾病风险正常化.
科学领域:
- 心血管医学 心血管医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 考虑到累积的吸烟暴露,戒烟与心血管疾病 (CVD) 风险之间的关系尚不清楚.
- 了解这种关联对于公共卫生计划和患者咨询至关重要.
研究的目的:
- 调查戒烟,累积吸烟史和心血管疾病风险之间的联系.
- 分析自戒烟以来的时间如何影响心血管疾病风险.
主要方法:
- 一项使用韩国国家医疗保险服务数据库 (2006-2019) 的回顾性队列研究.
- 根据自我报告的习惯将参与者分为现有,前任和从未吸烟者.
- 随着时间的推移,追踪吸烟状况和心血管疾病发病率 (心血管死亡,心肌梗塞,中风,心力衰竭).
主要成果:
- 在吸烟和发生心血管疾病之间观察到剂量依赖的关系.
- 低累积吸烟负担 (<8包年) 的前吸烟者在10年内显著降低心血管疾病风险,接近从未吸烟者的风险.
- 严重的前吸烟者 (≥8包年) 的心血管疾病风险下降速度较慢,需要超过25年才能达到与从未吸烟者相当的水平.
结论:
- 戒烟有利于心血管疾病风险,轻度吸烟者相对较快地达到接近正常的风险水平.
- 具有大量吸烟史的个人需要更长的戒烟期,以便他们的心血管疾病风险大幅度降低.
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