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相关实验视频

Updated: Jun 8, 2025

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
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机器人可操纵的内成像探针与侧面视图的3D光声学计算机断层扫描.

Yongjian Zhao, Zonglin Li, Li Liu

    Optics letters
    |November 1, 2024
    PubMed
    概括

    开发了一种新型的机器人内光内光学断层扫描探针,用于胃肠道癌症查. 该系统成功地局部化了病变,并在幻影研究中表征了异常,显示了临床潜力.

    科学领域:

    • 生物医学工程 生物医学工程
    • 医疗成像医学成像
    • 机器人技术 机器人技术 机器人技术

    背景情况:

    • 早期发现胃肠道癌症对于改善患者的治疗结果至关重要.
    • 目前的内镜成像方法在检测深层或微妙异常方面存在局限性.
    • 光声断层扫描 (PAT) 技术的进步为提高地表组织结构的可视化提供了潜力.

    研究的目的:

    • 开发和验证一种新型的连续机器人控制的内光体体积光声断层扫描 (vPAT) 探针.
    • 将定制的压电微机超声波传感器 (PMUT) 集成到一个紧的内镜系统中.
    • 评估系统在早期检测和描述胃肠病变方面的能力.

    主要方法:

    • 在12毫米直径,30毫米长的外内开发同轴光学和声学成像系统.
    • 设计和集成一个定制的PMUT用于声学检测.
    • 连续机器人运动能力的建模和描述,用于精确的探头方向.
    • 使用幻影研究进行验证,以模仿胃肠组织和病变.

    主要成果:

    • 成功开发了一个紧的,机器人驾驶的内膜发光管vPAT探头.
    • 具备准确模拟和控制连续机器人运动的能力.

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  • 幻影研究证实了该系统在早期癌症检测和查方面的潜力.
  • 机器人辅助系统有效地定位了未知的病变,并特征了深层次的异常.

    • 结论:

    • 开发的机器人内光内膜vPAT探针代表了内镜成像技术的重大进步.
    • 该系统在早期检测和描述胃肠道癌症方面显示出有前途的能力.
    • 需要进一步的临床研究来探索其在患者护理中的全部潜力.