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Updated: Jun 22, 2026

In utero Electroporation followed by Primary Neuronal Culture for Studying Gene Function in Subset of Cortical Neurons
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在APP/PS1小鼠天体细胞的转录组变化导致早期产后轴突初始段的结构变化.

María José Benitez1,2, Diana Retana1, Lara Ordoñez-Gutiérrez3,4

  • 1Instituto Cajal, CSIC, Madrid, Spain.

Cellular and molecular life sciences : CMLS
|November 1, 2024
PubMed
概括

早期阿尔茨海默氏病 (AD) 的变化涉及影响轴突初始段 (AIS) 的天体细胞变化. 这项研究揭示了质细胞对神经元功能产生影响,为AD提供了新的治疗点.

关键词:
在此之前,ADNP是ADNP.在AnkyrinG中使用Ankyrin星球细胞是星球细胞.阿克森的初始细分市场是Axon的初始细分市场.神经退行发生神经退行.这是一个P2X7的P2X7.雷蒂诺酸是什么意思 雷蒂诺酸是什么意思

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PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...