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致病性线粒体DNA突变抑制黑色素瘤转移

Spencer D Shelton1, Sara House1, Luiza Martins Nascentes Melo2

  • 1Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science advances
|November 1, 2024
PubMed
概括

线粒体DNA (mtDNA) 突变会影响癌症. 功能性mtDNA支持黑色素瘤生长和转移,而突变阻碍了瘤细胞的循环,并促进了对它们的选择.

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