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Updated: Jun 8, 2025

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通过跨区域的组合性突变发生增强3α-hydroxysteroid脱酶的特定活性

Siqi Ma1, Musen Li2, Shengheng Yan2

  • 1The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

International journal of biological macromolecules
|November 1, 2024
PubMed
概括

研究人员通过组合性突变发生增强了3α-Hydroxysteroid脱酶 (3α-HSD) 的活性. 最佳突变体的特定活性增加了6.85倍,改善了胆酸测量和生物技术应用.

关键词:
在3α-HSD中.跨区域的组合性突变发生.QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM具体活动 具体活动 具体活动

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