非输入管外体膜氧化的利用和结果,作为通往肺移植的桥梁
Alice L Zhou1, Maria R Jennings1, Armaan F Akbar1
1Division of Thoracic Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland.
概括
非输管外体膜氧化 (ECMO) 作为通往肺移植的桥梁,改善了外科手术后的结果和短期生存率. 这种方法应该考虑符合条件的肺移植候选人,需要ECMO支持.
科学领域:
- 心脏病学和肺病学.
- 移植医学 移植医学
- 关键护理医学 关键护理医学
背景情况:
- 体外膜氧化 (ECMO) 越来越多地用于严重的呼吸衰竭.
- 关于ECMO作为通往肺移植的桥梁的作用的数据有限.
研究的目的:
- 评估非输管ECMO桥接到肺移植的结果.
- 为了比较仅ECMO和ECMO与机械通风 (MV) 组之间的术后和生存结果.
主要方法:
- 在2005年5月至2023年3月期间,使用UNOS数据库对成年肺移植接受者进行了分析,这些接受者与ECMO建立了桥梁.
- 分类为ECMO+MV和仅ECMO的组.
- 移植后输入管道,72小时使用ECMO,停留时间和生存率的比较.
主要成果:
- 仅接受ECMO的患者年龄较大,缺血时间较短,肺部分配得分相似.
- 仅ECMO组的72小时输管率较低,住院时间较短.
- 仅ECMO组的90天生存率更高,与1年和5年生存率相似.
结论:
- 非输管ECMO桥接到肺移植与改善的术后结果有关.
- 这种策略表明,增强了短期生存率.
- 对于需要ECMO支持的肺移植候选人,应考虑非输管ECMO.
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