Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Quantifying treatment-related travel burden and its association with mortality in pediatric cancer: An analysis of state cancer registry data.

Cancer epidemiology·2026
Same author

Polarisome core component FgPea2 regulates FgBoi2-mediated polarized growth, pathogenicity and environmental stress in Fusarium graminearum.

Stress biology·2026
Same author

Genetic diversity analysis and core collection construction of Macadamia spp. from Yunnan using fourfold degenerate SNP sites.

BMC plant biology·2026
Same author

Case Report: Extracorporeal membrane oxygenation in acute coronary syndrome: a rare case of massive left ventricular thrombus.

Frontiers in cardiovascular medicine·2026
Same author

Exploring the Differences in Alkaloids of Fritillariae Thunbergii Bulbus From Different Regions Using Liquid Chromatography-Mass Spectrometry and Chemometrics.

Chemistry & biodiversity·2026
Same author

A comprehensive narrative review of <i>Epimedium</i> and its bioactive compounds in respiratory diseases.

Journal of pharmaceutical analysis·2026

相关实验视频

Updated: Jun 8, 2025

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

13.8K

聚合物人造心脏门来自改性二醇基聚碳酸聚氨.

Yage Hu1, Yao Xiong1, Yuan Wei1

  • 1National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610064, PR China.

Acta biomaterialia
|November 1, 2024
PubMed
概括

新的聚碳酸聚氨 (SiPCU) 增强了人造心脏门材料. 这些SiPCU提供了更好的生物稳定性,生物相容性和机械性能,比目前的门技术更有前途.

关键词:
生物相容性 生物相容性生物稳定性 生物稳定性心脏门的心脏门修改的宏分子二醇.聚碳酸聚氨聚碳酸.

更多相关视频

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.5K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

2.8K

相关实验视频

Last Updated: Jun 8, 2025

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

13.8K
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.5K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

2.8K

科学领域:

  • 生物材料科学 生物材料科学
  • 聚合物化学 聚合物化学
  • 心血管工程 心血管工程

背景情况:

  • 人工心脏门对于治疗心脏膜疾病至关重要.
  • 基于聚氨的材料为门应用提供耐用性,生物相容性和可调节性质.
  • 现有材料在生物稳定性,降解后的机械完整性和生物相容性方面面临限制.

研究的目的:

  • 为了合成和表征新型聚碳酸聚氨 (SiPCU) 用于人工心脏门的传单.
  • 提高聚氨弹性体的生物稳定性,机械性能和生物相容性.
  • 评估SiPCU与当前生物假体心脏门材料的性能.

主要方法:

  • 通过将4,4'-二环甲二酸 (HMDI) 纳入软段 (PCDL) 并使用HMDI与链延长器 (1,4-butanediol,BHTD) 用于硬段来合成SiPCU.
  • 具有特征的物理化学性质,氧化降解稳定性和降解后的机械性能.
  • 与Glut-PP相比,评估了生物相容性,血栓抵抗,化和内皮细胞粘附.
  • 制造并测试了用于血液动力学性能的门原型.

主要成果:

  • 合成的PHC-PCUB证明了改进的相混合,减少了聚甲基西洛 (PDMS) 引入的问题.
  • 材料表现出良好的物理化学特性,长期氧化降解稳定性,降解后最小的机械损失.
  • 与Glut-PP相比,PHC-PCUB显示了增强的生物相容性,优越的血栓阻力,减少化和增加内皮细胞粘附.
  • 门原型表现出更好的血液动力学性能.

结论:

  • 聚碳酸聚氨 (SiPCU) 是人工心脏门传单的一个有前途的先进材料.
  • 开发的SiPCU提供了卓越的生物稳定性,机械弹性和生物相容性的组合.
  • 这些材料有效地解决了当前机械和生物假体心脏门的局限性,为改善临床结果铺平了道路.