基于深度学习的前腔尺寸规范数据库用于角度闭关评估:新加坡中国眼睛研究
Zhi-Da Soh1, Mingrui Tan2, Zann Lee1
1Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
The British journal of ophthalmology
|November 1, 2024
概括
确定前段光学相干断层扫描 (ASOCT) 测量的规范分布有助于检测初级角度闭合疾病 (PACD). 特定的前腔深度 (ACD) 和透镜 (LV) 百分位数显示出PACD检测的希望.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 生物识别仪表是如何使用的
背景情况:
- 前段光学连贯性断层扫描 (ASOCT) 测量缺乏临床背景,限制了实用性.
- 建立规范性数据对于准确解释ASOCT调查结果至关重要.
- 通过标准化的测量语境,可以改善初级角闭合疾病 (PACD) 的检测.
研究的目的:
- 使用ASOCT. 确定前腔深度 (ACD),面积 (ACA),宽度 (ACW) 和透镜 (LV) 的规范分布.
- 应用这些参数的百分点切线来检测初级角度关闭疾病 (PACD).
- 评估ASOCT参数在识别PACD的诊断性能.
主要方法:
- 使用了来自新加坡中国眼睛研究的Visante ASOCT扫描.
- 眼睛不包括之前的眼睛手术,激光手术或创伤.
- 采用深度学习算法进行ASOCT测量,并使用开角眼睛建立规范数据.
主要成果:
- 分析了2157只眼睛 (1853个开角,304个闭角).
- ACD,ACA和ACW随着年龄的增长而下降,女性较小;LV显示相反的趋势 (p<0.022).
- 在ACD第20个百分位数和LV第85个百分位数中,PACD检测的高平衡精度 (分别为84.4%和84.2%) 超过了多变量回归模型.
结论:
- 前腔的参数根据年龄和性别有所变化.
- ACD的第20个百分位和LV的第85个百分位可以单独或组合用于PACD检测.
- 这些百分点切线在缺乏复杂的分类算法的情况下,为PACD查提供了可行的替代方案.
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