EKFC,.

Felipe Kenji Nakano1,2, Anna Åkesson3,4, Jasper de Boer5,6

  • 1Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium. felipekenji.nakano@kuleuven.be.

Scientific reports
|November 2, 2024
PubMed
概括

与欧洲功能联盟 (EKFC) 方程相比,机器学习 (ML) 模型在预测功能方面表现出竞争力. 随机森林 (RF) 在12岁以下的儿童中略高于EKFC的表现,这表明ML ML.

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The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production occurs. A nephron has two main components: a renal corpuscle and a renal tubule.
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The Glomerular Filtration Rate (GFR) is a measure of kidney function, reflecting the volume of filtrate formed per minute in the kidneys. On average, GFR is approximately 125 mL/min in males and 105 mL/min in females. Maintaining a relatively constant GFR is essential for the kidneys to effectively regulate body fluid homeostasis and maintain extracellular stability.
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Factors Affecting Renal Clearance: Renal Impairment

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