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Updated: Jun 8, 2025

Isolation of Murine Retinal Endothelial Cells for Next-Generation Sequencing
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Published on: October 11, 2021

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通过CDK6介导的内皮细胞周期加速驱动在遗传性出血性telangiectasia中的动脉静脉形

Sajeth Dinakaran1,2, Sima Qutaina1,2, Haitian Zhao1

  • 1Litwin-Zucker Alzheimer's Research Center, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.

Nature cardiovascular research
|November 2, 2024
PubMed
概括

遗传性出血端膜切除症 (HHT) 涉及到内皮细胞增多. 这项研究揭示了循环素依赖性激酶6 (CDK6) 驱动HHT中的细胞循环问题,这表明CDK4/6抑制剂可以治疗AVMs.

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In Vitro Three-Dimensional Sprouting Assay of Angiogenesis Using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing

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