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Updated: Jun 8, 2025

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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危哺乳动物中有害突变的遗传联系不平衡

Chunyan Hu1,2, Gaoming Liu1, Zhan Zhang1,2

  • 1Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.

EMBO reports
|November 2, 2024
PubMed
概括

新的统计数据,LDcor和nLDcor,检测到有害突变链接不平衡跨物种. 这有助于评估临灭绝的哺乳动物的遗传负担,揭示了老虎和大猩猩等物种的各种选择模式.

关键词:
有害的突变 有害的突变链接不平衡 链接不平衡负选择 负选择临灭绝的哺乳动物

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