临床分析和确定患有结肠的儿科患者
Yaying You1,2,3, Yijing Tao1,2,3, Yanwen Xu1
1Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
BMC pediatrics
|November 2, 2024
概括
炎症性肠病 (IBD) 占儿科结肠的不到一半. 关键指标,如体重减轻,周病变和特定的血液标记,有助于区分IBD与儿童的其他疾病.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 内部医学 内部医学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 许多疾病可以模仿炎症性肠病 (IBD).
- 对儿童结肠的准确诊断至关重要,以避免误诊.
- 这项研究的重点是将IBD与儿科患者结肠的其他原因区分开来.
研究的目的:
- 确定临床,实验室和内镜指标,以区分儿科炎性肠病 (IBD) 和其他导致结肠的原因.
- 为了降低患有结肠的儿童的误诊率.
主要方法:
- 在86名儿科患者的回顾性分析中,结肠镜检测到结肠.
- 在IBD和非IBD组之间比较临床特征,实验室发现,内镜特征和组织病理学.
- 多变量分析以确定儿科IBD与结肠的显著诊断预测因素.
主要成果:
- 炎症性肠病 (IBD) 仅在43%的患有结肠的儿科患者中被诊断出.
- 患有IBD的儿童的体重减轻率较高,周病变,口腔以及炎症标志物 (如NLR,ESR,CRP) 的升高.
- 在儿科IBD患者中观察到较低的血红蛋白和白蛋白水平. 血红蛋白,NLR,病得分和伪多是诊断儿科IBD的重要预测因素.
结论:
- 一些指标,包括临床症状,实验室标记物 (血红蛋白,NLR) 和内镜检测结果 (痕得分,伪多),可以帮助谨慎诊断儿科IBD.
- 将IBD与其他导致儿童结肠的疾病区分开来,需要对这些潜在指标进行全面评估.
更多相关视频
相关概念视频
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
145
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
145
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
89
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
89
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
321
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
321
01:25Assessment of the Rectum and Anus
160
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
160
01:21Inflammatory Bowel Disease V: Surgical Management
123
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
123
01:25Endoscopic Procedures II: Colonoscopy
57
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
57