同时存在的甲状腺腺瘤,甲状腺癌和甲状腺结核:一个病例报告
Adarsh Pratap Singh1, Biswarup Pramanik2, Arshi Tandon3
1Department of Surgery, AIIMS, New Delhi, India. aadarsh202@gmail.com.
Journal of medical case reports
|November 2, 2024
概括
本案例报告详细介绍了一例罕见的45岁女性,她同时患有甲状腺腺瘤,甲状腺癌和甲状腺结核病. 治疗包括为腺瘤和癌瘤进行手术,以及为结核病服用抗结核药物,从而缓解症状.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
背景情况:
- 甲状腺腺瘤,甲状腺癌和甲状腺结核病的同时存在非常罕见.
- 初级甲状腺结核不常见,通常在术后诊断出来.
- 虽然甲状腺癌与肺结核或甲状腺腺瘤之间存在关联,但这是第一次报告这三种疾病同时发生的病例.
研究的目的:
- 报告同步副甲状腺腺瘤,甲状腺癌和甲状腺结核病的独特病例.
- 调查慢性炎症 (甲状腺结核病) 与恶性瘤和副甲状腺腺瘤的发展之间的潜在联系.
- 为患有甲状腺功能低下症和这些共同存在的疾病的患者提供未来管理策略的见解.
主要方法:
- 一名45岁的女性患有甲状腺功能低下症,出现部胀和骨头疼痛.
- 调查显示高血症,副甲状腺激素升高,甲状腺结节.
- 进行了外科整体甲状腺切除术与副甲状腺切除术,随后进行了组织病理学分析和抗结核疗法.
主要成果:
- 组织病理学证实了亚急性粒状甲状腺炎,状细胞变化,乳头甲状腺微瘤和带有酸性细菌 (甲状腺结核病) 的结核性表皮质颗粒瘤.
- 切除的副甲状腺被确定为腺瘤.
- 在6个月的随访期间,患者从骨头疼痛中获得了显著的缓解,并且能够很好地容忍抗结核治疗.
结论:
- 甲状腺腺瘤,非骨髓性甲状腺癌和甲状腺结核病的同时发生非常罕见.
- 手术干预对甲状腺功能过高和甲状腺癌是有效的,而抗结核药物对甲状腺结核病有治愈作用.
- 潜在结核病的慢性炎症可能会导致甲状腺癌和甲状腺腺瘤的发展,这需要进一步研究潜在机制和最佳患者管理.
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