选择性卵子冷的简单而实用的方法,以控制成本并扩大获得护理的机会
Raoul Orvieto1,2,3, Norbert Gleicher4,5,6,7
1Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat Gan, Israel. Raoul.orvieto@sheba.health.gov.il.
Journal of ovarian research
|November 2, 2024
概括
为可负担性和可访问性,制定选择性卵子冷 (EEF) 的标准协议至关重要. 一种特定的卵巢刺激 (OS) 方法最大限度地提高了卵子产量,同时确保了安全性并减少了周期数.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 辅助生殖技术 辅助生殖技术
背景情况:
- 社会选择性卵子冷 (EEF) 在全球越来越受欢迎.
- 高昂的成本和有限的保险覆盖面对许多女性来说都是可访问性的重大障碍.
- 目前还没有针对EEF的标准化,具有成本效益的协议.
研究的目的:
- 在EEF中定义一个用于卵巢刺激 (OS) 的实用,标准化的协议.
- 为了最大限度地提高每个OS周期的卵细胞产量.
- 为了确保患者的安全,并尽量减少所需的OS循环的数量.
主要方法:
- 进行了叙事文学评论.
- 对EEF的卵巢刺激协议的相关文章进行了分析.
- 评估了关键参数,包括淋巴激素剂量,LH补充剂和触发方法.
主要成果:
- 对大多数女性来说,建议使用多剂量GnRH抗剂协议,每天服用300 IU的淋巴激素 (recFSH).
- 补充LH应与GnRH抗剂同时使用.
- 建议在最终的卵泡成熟时使用GnRH激动剂触发剂,在特定的患者群体中考虑双触发剂 (hCG) 和卡伯戈林.
结论:
- 在EEF中,确定的协议优化了卵细胞产量和患者安全.
- 标准化OS协议可能会降低成本并提高EEF的效率.
- 本协议为执行EEF的临床医生提供了实际指导方针.
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