在失眠中,慢波睡眠与血压之间的关联与失眠有关
Rong Ren1, Ye Zhang1, Xujun Feng1
1Sleep Medicine Center, Mental Health Center, Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Sleep
|November 2, 2024
概括
失眠患者缓慢波睡眠 (SWS) 的减少显著增加了早晨高血压的风险,特别是在男性中. 这种关联是剂量依赖的,突出显示SWS是高血压发展的关键因素.
科学领域:
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
- 高血压研究 高血压研究
背景情况:
- 失眠经常与客观睡眠异常有关,包括睡眠时间缩短和慢波睡眠 (SWS).
- 之前的研究表明,失眠患者的睡眠时间减少与高血压风险增加之间存在关联.
研究的目的:
- 在被诊断为失眠的患者中,研究慢波睡眠 (SWS) 和早上和晚上血压 (BP) 水平之间的关系.
主要方法:
- 对229名正常睡眠者和1378名失眠患者 (症状≥6个月) 进行了多睡眠扫描.
- 参与者根据他们的SWS百分比被分为四分之一.
- 高血压的定义是通过在聚睡眠学之前和之后进行的血压测量.
主要成果:
- 失眠患者的小于3.5%的SWS显著增加了早晨高血压的几率 (OR 3.27).
- 那些3.5%-10.2%的SWS的人也增加了早晨高血压的几率 (OR 2.38).
- 降低SWS和早晨高血压之间的关联仅在男性中显著,这表明性别特异性影响.
结论:
- 缓慢波睡眠 (SWS) 的减少是失眠患者上午高血压的重要危险因素.
- 这种关系是剂量依赖的,较低的SWS百分比与更高的高血压风险相关.
- 患有失眠和减少SWS的男性特别容易患上早晨高血压.
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