确定室内环境中异酸盐的暴露途径和风险评估
Yuna Kakimoto1, Kazushi Noro2, Qi Wang3
1Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Archives of environmental contamination and toxicology
|November 2, 2024
概括
像婴儿椅和床这样的家用产品会释放异酸盐,在室内造成健康风险. 多二酸和甲基异酸是关键问题,吸入空气是儿童的主要暴露途径.
科学领域:
- 环境化学环境化学
- 职业健康 职业健康 职业健康
- 毒理学 毒理学 毒理学
背景情况:
- 异酸盐是聚氨,涂料和建筑材料的关键工业化学品.
- 暴露于异酸盐可以导致严重的健康问题,包括呼吸道刺激,喘和病房综合征.
- 有限的研究存在于室内异酸盐来源和相关的健康风险.
研究的目的:
- 识别室内环境中异酸盐的来源和暴露途径.
- 评估室内异酸盐所带来的潜在健康风险.
- 在家用产品,尘埃和空气中量化异酸盐度.
主要方法:
- 在各种家用产品 (婴儿椅,床,喷雾泡) 中分析异酸盐度.
- 测量这些产品的异酸盐排放率.
- 在室内尘埃和空气样本中量化异酸盐.
- 估计人类暴露路径和风险评估.
主要成果:
- 家庭用品,如婴儿椅,床和喷雾泡被确定为室内显著的异酸 (ICA) 来源.
- 产品中的异酸盐度在38.2至1570 ng g-1.1之间.
- 从产品中持续观察到ICA的排放率 (0.05361.37 ng g-1 d-1).
- 室内尘埃和空气样本显示出不同水平的异酸盐,ICA是突出的.
- 吸入空气被确定为人类的主要暴露途径.
结论:
- 常见的家用产品已被证实是室内异酸盐的来源,有助于潜在的健康危害.
- 甲基异酸盐和多二异酸盐在室内环境中存在相当大的风险.
- 儿童可能因吸入空气而暴露于甲基异酸盐和二酸盐而面临重大风险.
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