在Hidradenitis Suppurativa中的公平性和结果事件:探索与现实世界诊断延迟相关的效果修饰器
Nicole Murray1, Isabel Truman2, Gary Milligan3
1Novartis Corporate Center (NOCC), Dublin, Ireland.
Dermatology and therapy
|November 2, 2024
概括
补腺炎 (HS) 诊断因误诊和患者尬等因素而显著延迟. 本研究确定了诊断延迟的关键驱动因素,以改善患者的治疗结果.
科学领域:
- 皮肤病学 皮肤病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 补腺炎 (HS) 患者在症状发作后平均面临7-10年的诊断延迟.
- 这些延迟的原因尚不清楚,这促使对医疗保健系统公平因素的调查.
研究的目的:
- 从医疗保健系统的公平性角度调查腹炎 (HS) 诊断延迟的驱动因素.
- 确定影响从症状出现到诊断的时间以及从第一次咨询到诊断的时间的因素.
主要方法:
- 一项文献审查确定了与延迟HS诊断相关的因素.
- 分析了来自Adelphi HS疾病特定计划 (DSP) TM (法国,德国,意大利,西班牙,英国,美国,2020/2021) 的临床和人口统计数据.
- 使用统计建模来评估影响诊断延迟的因素.
主要成果:
- 影响延迟的因素包括错误诊断,延迟的专家转诊和患者的尬.
- 年龄较大,白人族裔以及居住在德国的情况与症状发作延迟的减少有关.
- 吸烟,并发症和家族病史与更长的诊断延迟有关.
- 咨询后更快的诊断与年龄较大和家族病史有关.
- 更高的BMI,多种并发症,就业和多位医生与更长的延误有关.
结论:
- 通过真实世界的数据分析,已经确定了影响及时诊断HS的多个因素.
- 这项研究首次量化了这些修饰物的相对影响.
- 结果为有针对性的干预提供了洞察力,以加快诊断和改善疾病结果.
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