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五周间歇性暴露于交替冷和热刺激的手,并没有改变手指冷诱导的血管扩张反应

Roger Kölegård¹, Lena Norrbrand¹, Ola Eiken¹

¹Division of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden; Division of Environmental Physiology, Swedish Aerospace Physiology Center, KTH Royal Institute of Technology, Stockholm, Sweden.

Journal of thermal biology

|November 2, 2024

概括

这项研究发现,5周间歇性热刺激方案没有改善手指寒冷诱导血管扩张 (CIVD) 反应. 虽然感冒疼痛的感觉减少了,但温度反应能力和血液流量保持不变.

科学领域:

身体生理学身体生理学
热调节热调节热调节
血管生物学血管生物学

背景情况:

指冷诱导血管扩张 (CIVD) 反应对于预防感冒损伤至关重要.
间歇性接触热刺激是一种增强血管反应的潜在方法.
了解调节CIVD的因素对于职业和娱乐寒冷暴露很重要.

研究的目的:

为了调查长时间间歇性暴露于交替冷和热刺激的手是否会增强手指冷诱导血管扩张 (CIVD) 反应.
评估5周热刺激方案对手指皮肤温度和局部降温期间CIVD事件的影响.
为了评估寒冷引起的疼痛感觉和臂动脉流量介导扩张的变化.

主要方法:

八名健康男性接受了为期5周的治疗方案,包括每周三次在8°C和43°C的水中间歇性地浸泡60分钟的手.
手指皮肤温度和CIVD事件在治疗方案前后的两个30分钟冷挑试验 (8°C) 中被测量.
在暴露的手臂中评估了手臂动脉的流媒体扩张.

主要成果:

五周的治疗方案没有显著改变手指平均皮肤温度或暴露 (EXP) 或控制 (CON) 手中CIVD事件的发生率.
在治疗后观察到过渡性缓解感冒引起的疼痛感觉 (p=0.02).
手臂动脉流介导扩张在干预后保持不变 (p=0.51).

结论:

五周间歇性暴露于交替的冷和热刺激并没有提高手指温度对持续局部感冒的反应能力.
该疗法没有改善感冒诱导血管扩张 (CIVD) 反应.
虽然感冒疼痛的感知可能会暂时减少,但与CIVD相关的血管温度调节功能没有受到显著影响.

关键词:

适应适应适应在CIVD中,您可以使用CIVD.形成对比的浴.习惯化习惯化是一种习惯.热适应热适应热适应热感知热感知热感知

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