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由于高血糖引起的脂质过氧化会破坏STAT4的稳定,并在2型糖尿病中损害抗病毒Th1反应

Victor Gray1, Weixin Chen1, Rachael Julia Yuenyinn Tan1

  • 1School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Cell metabolism
|November 2, 2024
PubMed
概括

2型糖尿病通过破坏T辅助1 (Th1) 细胞反应,损害抗病毒免疫力. 高血糖引起的代谢缺陷导致脂质过氧化,损害Th1功能必不可少的关键蛋白 (STAT4) 并增加感染严重程度.

关键词:
T助手 1 的反应.过高血糖症 (hyperglycemia) 是一种脂类过氧化过氧化蛋白质碳基化蛋白质的碳基化.2 型糖尿病 2 型糖尿病

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