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结合植物提取物对长期COVID的影响:一个探索性随机对照试验

Thitiya Lukkunaprasit¹, Patompong Satapornpong², Pongsiri Kulchanawichien³

¹Department of Pharmacy Administration, College of Pharmacy, Rangsit University, Pathum Thani, Thailand.

Complementary therapies in medicine

|November 2, 2024

概括

结合植物提取物 (CPE) 可能有助于减轻长期COVID症状,如疲劳和后炼不适. 这项研究发现,CPE对缓解症状有好处,尽管需要更多的研究.

科学领域:

药理学药理学是指药理学的学科.
草药是一种草药.
临床试验临床试验

背景情况:

长期COVID是一个重大的全球健康挑战.
开发了一种新的组合植物提取物 (CPE) 配方,用于潜在的长期COVID症状管理.
在CPE中包含Citrus aurantifolia,Tiliacora triandra,Cannabis sativa,Alpinia galanga,以及Piper nigrum. 这些植物的种类包括:

研究的目的:

评估组合植物提取物 (CPE) 在经历长期COVID症状的参与者中的疗效和安全性.
评估CPE对C-反应蛋白 (CRP) 水平和整体症状负担的影响.
研究CPE对长期COVID患者的康复率,生活质量和不良事件的影响.

主要方法:

一项随机,双盲,安慰剂对照试验与66名参与者进行.
参与者每天接受4500毫克CPE或安慰剂7天.
结果包括CRP的变化,总症状得分,症状严重程度,与健康相关的生活质量 (HRQOL) 和不良事件,使用新开发的长时间COVID症状问卷.

主要成果:

与安慰剂相比,CPE配方没有显著改变C反应蛋白 (CRP) 水平.
在CPE组中观察到总症状得分的显著降低.
在CPE组中,中度至重度疲劳和炼后不适 (PEM) 显著减少.

结论:

结合植物提取物 (CPE) 在缓解关键的长期COVID症状,特别是疲劳和PEM方面显示出潜在的益处.
发现CPE配方具有可接受的安全概况,大多数是轻微的不良事件.
建议进行进一步的大规模临床试验,以确认这些发现并验证长时间的COVID症状问卷.

关键词:

阿尔皮尼亚加兰加加兰加.大麻sativa是一种大麻.类植物 aurantifolia 类植物组合植物提取物植物提取物疲劳疲劳疲劳疲劳疲劳植物补充剂植物补充剂长时间的COVID.派珀尼格拉姆 (Piper nigrum) 是一个黑色的手.后COVID的情况运动后的不适.提利亚科拉 (Tiliacora) 是一个三角形.

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