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Updated: Jun 8, 2025

Light-driven Enzymatic Decarboxylation
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一种依赖的二次酒精脱酶的合理设计,以提高其用于α-基基生物合成的氧化活性

Wenwen Pei1, Xuewen Zhang2, Yan Zeng2

  • 1College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China; National Engineering Laboratory for Industrial Enzymes, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; National Technology Innovation Center of Synthetic Biology, Tianjin 300308, China.

International journal of biological macromolecules
|November 2, 2024
PubMed
概括

工程二次酒精脱酶 (SADH) 显示了14.2倍的活性增加,用于可持续的酸生产. 计算分析揭示了增强金属酶活性的分子机制.

关键词:
金属酶是一种金属酶.分子动力学模拟模型理性的设计理性的设计.二次性酒精脱酶的使用Zn(2+) 协调方式.α-Hydroxyketone 是一种氧化的化合物.

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