埃塞俄比亚的乳腺癌及其决定因素:系统审查和元分析
Adisu Tafari Shama1, Dufera Rikitu Terefa2, Adisu Ewunetu Desisa2
1Department of Public Health, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia adisuteferi1906@gmail.com.
BMJ open
|November 2, 2024
概括
在埃塞俄比亚,乳腺癌影响了五分之一的癌症患者. 关键的危险因素包括加工食品,高胆固醇,不活动以及家族病史,这凸显了人们需要更健康的生活方式选择的必要性.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 乳腺癌是一个重大的全球健康问题,是全球女性癌症发病率和死亡率的主要原因.
- 值得注意的是,缺乏详细介绍乳腺癌的流行率和决定因素的综合研究,特别是在埃塞俄比亚.
研究的目的:
- 进行系统性审查和元分析,以确定埃塞俄比亚乳腺癌的综合流行率.
- 确定与埃塞俄比亚人口乳腺癌相关的关键风险因素和决定因素.
主要方法:
- 在埃塞俄比亚进行的观测研究的系统审查和元分析.
- 从十七篇文章中提取了数据,其中包括24,435名参与者,使用Joanna Briggs Institute的元分析工具进行质量评估.
- 使用随机效应建模来估计聚合效应,并使用森林地块可视化结果.
主要成果:
- 在埃塞俄比亚的癌症患者中,乳腺癌发病率的综合流行率为20.58% (95% CI 17.25%, 23.90%).
- 重要决定因素包括消费包装食品 (POR=2.12),高胆固醇 (POR=4.08),身体不活动 (POR=3.27),高体重指数 (BMI) (POR=2.27),绝经后 (POR=2.25),癌症家族史 (POR=3.65),以及缺乏母乳养 (POR=2.76).
结论:
- 乳腺癌影响了埃塞俄比亚大量的癌症患者,五分之一以上的人受到影响.
- 鉴定出的风险因素强调了改变生活方式的重要性,包括改变对全身食品的饮食习惯,定期体力活动,以及对家族病史和更年期状况的认识.
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