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Updated: Jun 8, 2025

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
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构建生物带:在化学合成中进行快速毒性评估的在线平台

Dmitry S Boichenko1,2, Nikita I Kolomoets1, Daniil A Boiko1

  • 1Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia.

Journal of chemical information and modeling
|November 3, 2024
PubMed
概括

Build-a-bio-Strip是一个新的在线工具,用于快速评估化学过程毒性. 它有助于识别危险物质,并为可持续化学选择更安全的合成途径.

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相关概念视频

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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