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Updated: Aug 8, 2026

Immunofluorescence Microscopy of γH2AX and 53BP1 for Analyzing the Formation and Repair of DNA Double-strand Breaks
10:47

Immunofluorescence Microscopy of γH2AX and 53BP1 for Analyzing the Formation and Repair of DNA Double-strand Breaks

Published on: November 3, 2017

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在泌尿器膀癌预后中,BCL-2和γ-H2AX免疫染特征

Julia Ayumi Ikeda Kawasaki1, Lais Capelasso Lucas Pinheiro1, Isabely Mayara da Silva1

  • 1Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Londrina State University, Londrina, PR, Brazil.

Pathology, research and practice
|November 3, 2024
PubMed
概括

这项研究调查了在尿路膀癌 (UBC) 中的BCL-2和γ-H2AX蛋白表达. 两种蛋白质都没有与预后或复发相关,这表明它们不是适合UBC临床管理的标记物.

关键词:
灭症 (apoptosis) 是一种死亡的过程.基因组的不稳定性肌肉的入侵 肌肉的入侵蛋白质表达 蛋白质表达瘤的复发 瘤的复发

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Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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