在母乳养后的几年里,持续减少亚临床炎症
Miya Boelling1, Jiajie Pu1, Anthony J Hanley1,2,3
1Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Canada.
The Journal of clinical endocrinology and metabolism
|November 3, 2024
概括
至少3个月的纯母乳养与女性降低心血管风险有关. 较短的持续时间,特别是不到3个月,与较高的C-反应蛋白 (CRP) 水平有关,表明持续的炎症.
科学领域:
- 心血管健康的心血管健康
- 生殖健康 生殖健康
- 炎症研究的研究.
背景情况:
- 已知哺乳可以降低女性心血管疾病 (CVD) 风险.
- 这种心脏保护作用背后的具体机制在很大程度上是未知的.
研究的目的:
- 调查纯母乳养时间与心血管风险因素之间的关联.
- 在产后的前五年分析这些关联.
主要方法:
- 对328名女性进行前性队列研究.
- 连续的心脏代谢评估包括人体测量,血压,脂质,葡萄糖,脂肪素和C反应蛋白 (CRP) 在产后1,3年和5年.
- 妇女分为三个专属母乳养持续时间组:<3个月,3-6个月和≥6个月.
主要成果:
- 代谢综合征的患病率更高在妇女母乳养专为3个月相比较较长的持续时间5年分娩后 (14.0%对6.9%对4.2%).
- 在对共变量进行调整后,在血压,葡萄糖或脂质资料中没有发现显著差异.
- 在分娩后3年和5年,仅母乳养3个月的妇女表现出持续较高的CRP水平,表明持续的亚临床炎症.
结论:
- 短时间的纯母乳养 (<3个月) 与亚临床炎症的增加有关.
- 减少亚临床炎症可能是促进哺乳期心脏保护益处的关键机制.
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