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Updated: Jun 8, 2025

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在结直肠癌中,cGAS独立于STING通路调节代谢重编程

Fan Wang1, Chao Jiang1, Hong-Xia Hui1

  • 1Department of Medical Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an City, Jiangsu Province, 223300, China.

Experimental cell research
|November 3, 2024
PubMed
概括

循环GMP-AMP合成酶 (cGAS) 通过与NDUFA4L2相互作用,驱动结直肠癌 (CRC) 中的代谢重编程,独立于STING通路. 这种相互作用促进CRC细胞存活,并与预后不佳有关.

关键词:
结肠直肠癌是一种癌症.葡萄糖溶解是什么? 葡萄糖溶解代谢重编程是一种代谢重编程.氧化酸化是一种氧化酸化.cGAS-STING 的使用情况.

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